AKOS BRN-0541
4-Fluoro-3-(methoxycarbonyl)phenylboronic acid
CAS: 874219-35-9
Molecular Formula: C8H8BFO4
AKOS BRN-0541 - Names and Identifiers
| Name | 4-Fluoro-3-(methoxycarbonyl)phenylboronic acid |
| Synonyms | AKOS BRN-0541 3-Carboxy-4-Fluorophenylboroni METHYL 5-BORONO-2-FLUOROBENZOATE 4-FLUORO-3-METHOXYCARBONYLPHENYLBORONIC ACID 4-Fluro-3-Methoxycarbonylbenzene boronic acid 4-Fluoro-3-(methoxycarbonyl)phenylboronic acid 4-Fluoro-3-(methoxycarbonyl)benzeneboronic acid 4-FLUORO-3-(METHOXYCARBONYL)BENZENEBORONIC ACID |
| CAS | 874219-35-9 |
| InChI | InChI=1/C8H8BFO4/c1-14-8(11)6-4-5(9(12)13)2-3-7(6)10/h2-4,12-13H,1H3 |
AKOS BRN-0541 - Physico-chemical Properties
| Molecular Formula | C8H8BFO4 |
| Molar Mass | 197.96 |
| Density | 1.33±0.1 g/cm3(Predicted) |
| Melting Point | 253-255 |
| Boling Point | 364.8±52.0 °C(Predicted) |
| Flash Point | 174.405°C |
| Vapor Presure | 0mmHg at 25°C |
| pKa | 7.82±0.10(Predicted) |
| Storage Condition | Inert atmosphere,2-8°C |
| Refractive Index | 1.514 |
| MDL | MFCD06801688 |
AKOS BRN-0541 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Hazard Note | Irritant/Keep Cold |
| Hazard Class | IRRITANT |
AKOS BRN-0541 - Introduction
4-Fluoro-3-(methoxycarbonyl)phenylboronic acid(4-Fluoro-3-(methoxycarbonyl)phenylboronic acid) is an organic boronic acid derivative. Its chemical formula is C9H8BFO4 and its molecular weight is 214.97g/mol. The compound has the following properties:
Nature:
1. Appearance: white crystalline powder
2. Melting point: about 180-181°C
3. Solubility: Soluble in many organic solvents, such as dichloromethane, ether and chloroform
Use:
4-Fluoro-3-(methoxycarbonyl)phenylboronic acid is widely used in the field of organic synthesis. It can be used as a raw material for the synthesis of ringtones, and can also be used for ligand development and drug synthesis. As a boric acid compound, it can react with other organic compounds to form stable borate esters.
Preparation Method:
A common synthesis method is to transesterify p-methoxycarbonyl-p-succinic anhydride (dimethylsuccinate) and trimethylboronic acid (trimethylborate) to generate p-methoxycarbonyl-p-succinic acid (dimethyl 4-fluoro-3-(methoxycarbonyl)phenylsuccinate). Then, the reaction of the-methoxycarbonyl---succinic acid with an excess of boric acid or boric acid succinic ester, catalyzed by hydrochloric acid, yields 4-Fluoro-3-(methoxycarbonyl)phenylboronic acid.
Safety Information:
4-Fluoro-3-(methoxycarbonyl)phenylboronic acid has high security, but the following matters still need to be paid attention:
1. Avoid inhalation, chewing or contact with skin and eyes.
2. Wear appropriate personal protective equipment, including chemical protective glasses and gloves.
3. Operate in a well-ventilated place to avoid prolonged contact.
4. in case of misuse or contact, please seek medical attention immediately and take the product packaging to the hospital.
Nature:
1. Appearance: white crystalline powder
2. Melting point: about 180-181°C
3. Solubility: Soluble in many organic solvents, such as dichloromethane, ether and chloroform
Use:
4-Fluoro-3-(methoxycarbonyl)phenylboronic acid is widely used in the field of organic synthesis. It can be used as a raw material for the synthesis of ringtones, and can also be used for ligand development and drug synthesis. As a boric acid compound, it can react with other organic compounds to form stable borate esters.
Preparation Method:
A common synthesis method is to transesterify p-methoxycarbonyl-p-succinic anhydride (dimethylsuccinate) and trimethylboronic acid (trimethylborate) to generate p-methoxycarbonyl-p-succinic acid (dimethyl 4-fluoro-3-(methoxycarbonyl)phenylsuccinate). Then, the reaction of the-methoxycarbonyl---succinic acid with an excess of boric acid or boric acid succinic ester, catalyzed by hydrochloric acid, yields 4-Fluoro-3-(methoxycarbonyl)phenylboronic acid.
Safety Information:
4-Fluoro-3-(methoxycarbonyl)phenylboronic acid has high security, but the following matters still need to be paid attention:
1. Avoid inhalation, chewing or contact with skin and eyes.
2. Wear appropriate personal protective equipment, including chemical protective glasses and gloves.
3. Operate in a well-ventilated place to avoid prolonged contact.
4. in case of misuse or contact, please seek medical attention immediately and take the product packaging to the hospital.
Last Update：2024-04-09 02:00:48
Supplier List
Spot supply
Product Name: 4-Fluoro-3-methoxycarbonylphenylboronic acid Request for quotationCAS: 874219-35-9
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 4-Fluoro-3-(methoxycarbonyl)phenylboronic Acid Visit Supplier Webpage Request for quotationCAS: 874219-35-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 4-Fluoro-3-(methoxycarbonyl)phenylboronic Acid (contains varying amounts of Anhydride) Visit Supplier Webpage Request for quotationCAS: 874219-35-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 4-Fluoro-3-(methoxycarbonyl)phenylboronic Acid Visit Supplier Webpage Request for quotationCAS: 874219-35-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: 4-Fluoro-3-methoxycarbonylphenylboronic acid Request for quotationCAS: 874219-35-9
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 4-Fluoro-3-(methoxycarbonyl)phenylboronic Acid Visit Supplier Webpage Request for quotationCAS: 874219-35-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 4-Fluoro-3-(methoxycarbonyl)phenylboronic Acid (contains varying amounts of Anhydride) Visit Supplier Webpage Request for quotationCAS: 874219-35-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 4-Fluoro-3-(methoxycarbonyl)phenylboronic Acid Visit Supplier Webpage Request for quotationCAS: 874219-35-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History